FOXO4-DRI 2mg
Size: 2mg | 99% Purity
M.Wt: ~5850
Formula: Retro-inverso D-amino acid peptide
Solubility: H2O
Purity: >99%
Storage: -20°C / 3 years
Half life: Not established
| Purity (HPLC) | >99% |
|---|---|
| Molecular weight | ~5850 g/mol |
| Synonyms | FOXO4-DRI, FOX04-DRI, FOXO4 D-Retro-Inverso |
| Solubility | H2O |
| Storage | -20°C / 3 years |
Research reference: View mechanism, literature and identifier graph →
Reconstitution calculator (pre-filled for 2 mg)
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FOXO4-DRI 2mg — research reference material
FOXO4-DRI 2mg is supplied by NMChem as a research reference material in a 2mg presentation. Compound class: D-retro-inverso peptide · senolytic, characterised in the literature as a senolytic peptide. It is supplied strictly for in-vitro laboratory research and is not for human or veterinary use.
Research context
Senolytic peptide; studied in cellular-senescence research. Full mechanism detail, the identifier graph and selected peer-reviewed literature are set out on our FOXO4-DRI research reference. Related compounds in the same research area: Epitalon, MOTS-c. You can also compare it side by side on our comparison tool.
Presentation
This listing is the 2mg presentation at >99% stated purity, catalogue reference FOX2.
Identifiers
- Molecular weight: ~5850 g/mol
- Synonyms: FOXO4-DRI, FOX04-DRI, FOXO4 D-Retro-Inverso
- Class: D-retro-inverso peptide · senolytic
Format & quality
Supplied as 2mg at >99% purity. Identity and purity are characterised by reversed-phase HPLC and mass spectrometry, with a per-batch Certificate of Analysis available on request. This item is a lyophilised powder and requires reconstitution before use; bacteriostatic water is supplied separately, and our reconstitution guide covers volumes and concentrations. Solubility: H2O.
Storage
Store at -20°C, protected from light. Stated shelf life 3 years from date of manufacture. Always confirm against the Certificate of Analysis supplied with your batch.
Research use only — not for human or veterinary use, food, cosmetic or therapeutic application. NMChem supplies this item as a laboratory reference material; no dosing or administration guidance is provided.
Frequently asked questions
What is FOXO4-DRI 2mg?
D-retro-inverso peptide · senolytic. Senolytic peptide; studied in cellular-senescence research. NMChem supplies it as a research reference material only.
How should FOXO4-DRI 2mg be stored?
At -20°C, protected from light, with a stated shelf life of 3 years. The batch Certificate of Analysis is the controlling document.
Certificate of Analysis
Reconstitution
For peptides supplied as lyophilised powder, reconstitute in bacteriostatic water or sterile saline at the concentration appropriate to your protocol. Allow the vial to come to room temperature before opening, add solvent slowly down the inside wall (do not directly onto the powder), and gently invert until clear. Do not vortex.
Reconstituted solutions are typically stable at 2–8°C for the durations published in the corresponding peer-reviewed reference. For long-term storage, aliquot and freeze at −20°C; avoid repeated freeze–thaw cycles.
Research literature
Selected peer-reviewed publications from PubMed referencing this compound. Provided for research orientation — not an endorsement of any clinical application. Each citation links to the canonical PubMed record.
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FOXO4-DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation.
Kong YX et al. · Communications biology · 2025
PubMed PMID 39994346 -
FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion from Leydig cells.
Li Y et al. · Experimental gerontology · 2024
PubMed PMID 39025385 -
FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice.
Zhang C et al. · Aging · 2020
PubMed PMID 31959736
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