SLU-PP-332
Pan-ERR agonist / exercise-mimetic · research grade · per-batch COA. Research use only.
| Purity (HPLC) | >=98% |
|---|---|
| CAS number | 2438241-25-7 |
| Synonyms | SLU-PP-332 |
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COA and batch number on every vial.
SLU-PP-332 is a synthetic pan-ERR agonist — active at the estrogen-related receptor family — studied as an exercise-mimetic in metabolic and mitochondrial research. It is supplied by NMChem as a research reference material.
Not a peptide
Worth stating plainly, because it changes how the documentation should be read: SLU-PP-332 is a small molecule, not a peptide. It has no amino-acid sequence, it is not made by solid-phase synthesis, and the characteristic peptide impurities — deletion sequences, truncations, a trifluoroacetate counterion — do not apply to it.
Consequently the analytical picture differs. There is no net-peptide-content correction to make, and identity confirmation rests on mass together with structural methods rather than on sequence. HPLC purity remains the standard purity measure and is subject to the same limitations as for any other compound — it is a relative area percentage at one wavelength under one method, as covered in what HPLC purity actually means. The general reading order in how to read a Certificate of Analysis applies unchanged.
Presentation
SKU SLU332. Research reference material with a per-batch Certificate of Analysis available on request against the lot number on the vial. Batch numbers and traceability explains what that link is doing.
Related metabolic-research references: 5-Amino-1MQ, MOTS-c and AOD-9604.
Research use only. Supplied for in-vitro research and laboratory use. Not for human or veterinary use, not a medicine, and not for food or cosmetic application. See the compliance page for the framework NMChem operates under.
Certificate of Analysis
Reconstitution
For peptides supplied as lyophilised powder, reconstitute in bacteriostatic water or sterile saline at the concentration appropriate to your protocol. Allow the vial to come to room temperature before opening, add solvent slowly down the inside wall (do not directly onto the powder), and gently invert until clear. Do not vortex.
Reconstituted solutions are typically stable at 2–8°C for the durations published in the corresponding peer-reviewed reference. For long-term storage, aliquot and freeze at −20°C; avoid repeated freeze–thaw cycles.
Research literature
Selected peer-reviewed publications from PubMed referencing this compound. Provided for research orientation — not an endorsement of any clinical application. Each citation links to the canonical PubMed record.
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A Synthetic ERR Agonist Alleviates Metabolic Syndrome.
Billon C et al. · The Journal of pharmacology and experimental therapeutics · 2024
PubMed PMID 37739806 -
Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity.
Billon C et al. · ACS chemical biology · 2023
PubMed PMID 36988910 -
Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function.
Xu W et al. · Circulation · 2024
PubMed PMID 37961903 -
In Vitro Metabolism and Analytical Characterization of SLU-PP-332 and SLU-PP-915: Novel Pan-ERR Agonists With Doping Potential.
Möller T et al. · Rapid communications in mass spectrometry : RCM · 2026
PubMed PMID 41588687 -
Chemical optimization of the exercise mimetic SLU-PP-332 enables insight into estrogen-related receptor signaling.
Okda HE et al. · International journal of biological macromolecules · 2026
PubMed PMID 41850449 -
Analysis and Identification of In Vitro Metabolites of Exercise Mimetic SLU-PP-332 ERRα/β/γ Agonist for Doping-Control Purposes.
Avliyakulov NK et al. · Drug testing and analysis · 2026
PubMed PMID 41688415
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